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Cross-OS remote debugging
It would be extremely useful if PTVS supported remote debugging on non-windows machines.
The advantage of this would be being able to keep the platform independency of python - for example, a webapp i work on runs better on linux so I run it via WSGI/Apache on a linux system but access it through a SMB share from my windows machine. And even though that case might be a bit special I guess quite some users who work with multiple OSs would appreciate being able to use their favourite IDE even for debugging on the other OS.