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I would like to congratulate you for your effort and the pytools product!
I have a django project of 29+ django apps (150+ models). When I open the project the load time takes about 5+ minutes.
I am using vs 2012 pro,django 1.4.3 and python 2.7 on a I7-2720QM CPU (2.2GHz) with 8GB RAM and samsung 840 SSD disk. Everything runs from the SSD disk